What is Primary Sclerosing Cholangitis (PSC)?
Primary Sclerosing Cholangitis (PSC) is a chronic disease of the bile ducts in the liver which become inflamed and scarred and ultimately gets blocked. As the bile ducts get blocked, it accumulates in the liver and damages the liver cells causing cirrhosis or fibrosis. Liver cirrhosis impairs the liver function and finally totally damages the liver where the patient will need a liver transplant to survive.
PSC advances slowly and patients may have the disease for many years before it is even diagnosed. Most people with PSC ultimately require a liver transplant. PSC can also lead to bile duct cancer due to continuous inflammation and scarring. Constant monitoring with MRIs and endoscopy is absolutely essential to pick up cancer in the early stages.